Welcome to
Schurgers Lab
About Schurgers Lab
At Schurgers Lab, we are dedicated to unraveling the mechanisms behind vascular remodeling, ageing and calcification and its impact on cardiovascular health. Led by Professor Leon Schurgers, a renowned expert in vascular biology, our team focuses on understanding how vascular smooth muscle cells impact vascular disease associated with ageing, such as atherosclerosis, vascular stiffness, aortic valve disease and aneurym. By bridging basic science and clinical applications, we aim to develop innovative solutions for complex medical challenges.
Who works here?
Leon Schurgers
Cardiovascular cell biology and biochemistry
Rogier Veltrop
Molecular cell biologist
Nasim Bahram Sangani
Systems Biology and Molecular Neuroscience
Armand Jaminon
Assistant Professor, vascular smooth muscle cells in arterial remodeling and vascular calcification
Publication highlights
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling.
miR-24-3p secreted as extracellular vesicle cargo by cardiomyocytes inhibits fibrosis in human cardiac microtissues.
Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol.
Development of the BioHybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells and Blood to Measure Vascular Calcification Propensity.
Vitamin K-a neglected player in cardiovascular health: a narrative review.