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Publications
2025
Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor.
Authors:
Leon Schurgers
A randomized prospective crossover study on the effects of medium cut‑off membranes on FGF-23 and inflammatory mediators in patients receiving regular haemodialysis.
Authors:
Leon Schurgers
Resveratrol modulates phosphorylation of ERK and AKT in murine cementoblasts during in vitro orthodontic compression.
Authors:
Leon Schurgers
Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling.
Authors:
Leon Schurgers
Interpretation of intra-operative strain differences in ascending thoracic aortic repair patients.
Authors:
Leon Schurgers
2024
Gla-Rich Protein Is Associated with Vascular Calcification, Inflammation, and Mineral Markers in Peritoneal Dialysis Patients.
Authors:
Leon Schurgers
Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics.
Authors:
Leon Schurgers
Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension.
Authors:
Armand Jaminon
Leon Schurgers
Involvement of extracellular vesicle microRNA clusters in developing healthy and Rett syndrome brain organoids.
Authors:
Nasim Bahram Sangani
Changes in the gut microbiota of pseudoxanthoma elasticum patients.
Authors:
Leon Schurgers
A novel insight into neurological disorders through HDAC6 protein-protein interactions.
Authors:
Nasim Bahram Sangani
Mediterranean Diet Favors Vitamin K Intake: A Descriptive Study in a Mediterranean Population.
Authors:
Leon Schurgers
Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health.
Authors:
Rogier Veltrop
2023
Randomized Controlled Clinical Trial of the Effect of Treatment with Vitamin K2 on Vascular Calcification in Hemodialysis Patients (Trevasc-HDK).
Authors:
Leon Schurgers
Common Histological Features Suggesting Enchondral Ossification Pathways in Calciphylaxis of Various Origins: A Study of Human Subcutaneous Tissue Biopsies.
Authors:
Leon Schurgers
New Food Frequency Questionnaire to Estimate Vitamin K Intake in a Mediterranean Population.
Authors:
Leon Schurgers
Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs.
Authors:
Armand Jaminon
Leon Schurgers
Microvesicle-Mediated Tissue Regeneration Mitigates the Effects of Cellular Ageing.
Authors:
Leon Schurgers
Real world evidence: Perspectives from a European Society of Cardiology Cardiovascular Round Table with contribution from the European Medicines Agency.
Authors:
Rogier Veltrop
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair.
Authors:
Leon Schurgers
Application of the mineral-binding protein fetuin-A for the detection of calcified lesions.
Authors:
Armand Jaminon
Leon Schurgers
2022
Calcium Signalling in Heart and Vessels: Role of Calmodulin and Downstream Calmodulin-Dependent Protein Kinases.
Authors:
Armand Jaminon
Rogier Veltrop
Vitamin K1 and progression of cardiovascular calcifications in hemodialysis patients: the VitaVasK randomized controlled trial.
Authors:
Leon Schurgers
Integrating Mechanisms in Thrombotic Peripheral Arterial Disease.
Authors:
Leon Schurgers
Spatial multi-omic map of human myocardial infarction.
Authors:
Leon Schurgers
Vascular Smooth Muscle Cell Neutral Sphingomyelinase 2 in the Release of Exosomes and Vascular Calcification.
Authors:
Leon Schurgers
Nasim Bahram Sangani
Ageing - Oxidative stress, PTMs and disease.
Authors:
Leon Schurgers
Identification and characterization of post-translational modifications: Clinical implications.
Authors:
Leon Schurgers
Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.
Authors:
Leon Schurgers
Lipids and lipoproteins in cardiovascular diseases: a classification.
Authors:
Leon Schurgers
Influence of rivaroxaban compared to vitamin K antagonist treatment upon development of cardiovascular calcification in patients with atrial fibrillation and/or pulmonary embolism.
Authors:
Leon Schurgers
Nanoencapsulation of Gla-Rich Protein (GRP) as a Novel Approach to Target Inflammation.
Authors:
Leon Schurgers
Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease.
Authors:
Leon Schurgers
2021
The role of Extracellular Vesicles during CNS development.
Authors:
Nasim Bahram Sangani
Intravenous Vitamin K1 for the Correction of Prolonged Prothrombin Times in Non-Bleeding Critically Ill Patients: A Prospective Observational Study.
Authors:
Leon Schurgers
Intra-Operative Video-Based Measurement of Biaxial Strains of the Ascending Thoracic Aorta.
Authors:
Leon Schurgers
A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases.
Authors:
Leon Schurgers
Vitamin K in CKD Bone Disorders.
Authors:
Leon Schurgers